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Although extracellular-regulated kinase phosphorylated, MYC (V-Myc avian myelocytomatosis viral oncogene homolog) regulates endothelial metabolism and growth factor signaling for cell growth, proliferation, and anabolic metabolism [226, 227]

For instance, levomilnaciprans effects are associated with upregulation of the anti-aging protein -Klotho, which has downstream regulatory effects on oxidative stress and inflammation