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However, when Cys 129 residue of PTPN22 is mutated, the disulfide bond cannot form and the enzyme is exposed by oxidation, resulting in inactivation (93)

Recent studies have demonstrated that the occurrence of polycystic kidney disease is related to ferroptosis

Senescence signaling pathways in podocytes involve key mediators like p16 INK4A , p21, and p53, influencing cellular senescence, degeneration, and the expression of fibrogenic factors [48, 49]

The pathophysiology of anaemia in malaria is multifactorial, involving both haemolysis and decreased erythropoiesis (appendix p