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Intrinsically, melatonin promoted mitochondrial dysfunction, release of cytochrome c, and activation of caspase-9

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Holton KF (2021) Micronutrients may be a unique weapon against the neurotoxic triad of excitotoxicity, oxidative stress and neuroinflammation: a perspective

Testosterone deficiency, defined as levels below the normal physiological range, leads to symptoms such as reduced libido, ED, loss of muscle mass, decreased bone density, and fatigue [140]