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A study on the identification of DNMT1 inhibitors through a virtual screening showed that 6 induces antiproliferative effects in three different tumor cell lines ( in vitro assay using DNMT1 or DNMT3b showed that nanaomycin A selectively inhibits DNMT3b

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39 Available data show that OxPLs can activate dormant cells in the presence of stress hormones and polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC)

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One case report utilized KD (65% fat, 25% protein, 10% carbs) with a time-restricted feeding window in a 65-year-old woman with major depression and type II diabetes and reported remission of depression (PHQ-9 17 to 0), normalization of HbA1c, decrease in estimated average glucose from 216 to 96 mg/dL, improvement in HOMA-IR from 9.4 to 2.3, and TG/HDL ratio from 4.7 to 1.2 over 12 weeks