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a fluid), Archimedes' principle may be stated thus in terms of forces: Any object, wholly or partially immersed in a fluid, is buoyed up by a force equal to the weight of the fluid displaced by the object with the clarifications that for a sunken object the volume of displaced fluid is the volume of the object, and for a floating object on a liquid, the weight of the displaced liquid is the weight of the object

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This means the 10 to 200 mcg/kg doses that dominate the animal literature translate to a rough human equivalent of approximately 1.6 to 32 mcg/kg, or about 120 to 2,400 micrograms for a 75-kilogram adult

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40 They are mostly RCTs and/or have enrollments of at least close to 100, revealing the importance of rigorous research design and suggesting that trials on non-pharmacological interventions may require a relatively large sample size to identify the treatment effect