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Therefore, the identification of new drugs for this disease is indispensable

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Exploiting this structural feature led to the development of the PVIVIT peptide, a high-affinity optimized variant of the native NFAT PxIxIT motif that selectively inhibits NFAT-driven transcription [24,25]

However, infection can lead to serious complications in high-risk groups such as the elderly (131) and those with a compromised immune system (20) or chronic illnesses (132)

One commenter stated that this latter exclusion could have a not insignificant impact on therapeutic classes frequently administered by clinicians, such as oncology products

These findings further validate the absence of metallic Ru species in the Ru-hydroxide biocatalytic materials