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Furthermore, FMO3 is regulated by farnesoid X receptor (FXR), a nuclear receptor activated by bile acid (Lefebvre et al., 2009), and injection of FXR ligands induced the expression of FMO3 and the production of TMAO in mice (Bennett et al., 2013)

However, these large fatty acid molecules cannot simply diffuse into the mitochondria on their own

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Plants produce flavonoids, such as luteolin, as a cellular defense against pathogens or UV radiation