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The rare autosomal recessive disorder Immerslund-Grasbeck (IGS) disease is caused by mutations in either the gene Amnion Associated Transmembrane Protein (AMN) or Cubilin (CUBN) gene responsible for the synthesis of cubam receptors (Sobczynska-Malefora et al., 2021)

Because of the effort needed to reduce cyano B12 to an active form, its absorption rate varies greatly between people

Comprehensive preclinical safety evaluations across multiple animal models demonstrate favorable tolerability profiles with excellent safety margins for investigational research applications

Gruber, K., Puffer, B

B12 injections are elective wellness services

This condition, known as nighttime paresthesia , affects many people