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Moreover, gut dysbiosis can alter bile acid metabolism, leading to the accumulation of toxic bile acids in the liver (67)

Structural tissue-level changes develop over 612 weeks

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specifically, studies that bridge the gap between preclinical findings and human clinical outcomes

Sumrall ET, Shen Y, Keller AP, Rismondo J, Pavlou M, Eugster MR, Boulos S, Disson O, Thouvenot P, Kilcher S et al (2019) Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion