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Patients with diabetes mellitus treated with BOTOX were more likely to develop urinary retention than nondiabetics

The desensitisation procedure should be started by the 1/1001/1000 solutions of the drug target or the 1/101/1000 solutions of positive intradermal test dose and in increasing doses by doubling with 3090min intervals until the therapeutic dose is achieved.5 Desensitisation must be carried out in a hospital setting by experienced personnel with adequate resuscitation equipment readily available

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A few commenters specifically supported the proposal to update and codify CMS' ability to grant ECEs to hospitals, REHs, and ASCs even if those facilities have not requested an exception