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Inhibition of CD47 effectively targets pancreatic cancer stem cells via dual mechanisms

Annual review of medicine

Abbreviations HMs: Heavy metals Al: Aluminium Cd: Cadmium Mn: Manganese Pb: Lead Cr: Chromium ROS: Reactive oxygen species PCs: Phytochelatin HSPs: Heat shock proteins Ca: Calcium Mo: Molybdenum CAT: Catalase H 2 O 2 : Hydrogen peroxide APX: Ascorbate peroxidase AR: Arsenate reductase S: Sulphur SNP: Sodium nitroprusside JA: Jasmonic acid As: Arsenic Cu: Copper Co: Cobalt Ni: Nickel Hg: Mercury Mg: Magnesium GSH: Glutathione MT: Metallothionein (P): Phosphorus EL: Electrolytic leakage O 2 : Superoxide SOD: Superoxide dismutase MDA: Malondialdehyde GR: Glutathione reductase Se: Selenium Si: Silicon NPs: Nanoparticles RWC: Relative water content References Abbas S, Basit F, Tanwir K et al (2023) Exogenously applied sodium nitroprusside alleviates nickel toxicity in maize by regulating antioxidant activities and defense-related gene expression

Taken in the usual therapeutic doses, it is conjugated with glucuronic acid or sulfate, which is then excreted by the kidneys

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For topical collagen, choose products that are FDA-approved and suitable for your skin type to help prevent irritation or allergic reactions