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It serves as a crucial component in fatty acid transport, stimulates the transfer of long-chain fatty acids into the mitochondria, where they undergo -oxidation to create acetyl-CoA, a precursor for ATP synthesis via the tricarboxylic acid cycle (TCA cycle) [5, 6, 26]

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The wild allele is the most detrimental, increasing the rate of alcohol conversion to acetaldehyde by up to 70%