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Am J Phys Regul Integr Comp Phys 284(4):R893R912 Weir MR, Dzau VJ (1999) The renin-angiotensin-aldosterone system: a specific target for hypertension management

Endotoxin: Less than 0.05 ng/g (0.5 EU/g) as determined by LAL test

Reversible HPA axis (adrenal function) suppression may result from exposure to the topical corticosteroid, uocinolone acetonide, so discontinue use if signs and symptoms of this condition occur

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Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3