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Description

These stressors create oxidative stress a state where damaging molecules called free radicals outpace the bodys antioxidant defenses

Research Stage: Preclinical only

Hargreaves KM, Pardridge WM

Cell 2014

By combining the micro-spectrophotometry and a proton-selective microelectrode analysis, we identified a significant difference in pHv between the blue and red protoplasts (4.1 and 3.3, respectively) 9

Pyrroline-5-carboxylic acid reductase 1 (PYCR1) has been identified as a key player in the progression of lung cancer, functioning through a metabolic linkage between proline and glutamine