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Interestingly, we see marginal release of cytochrome c following 5FU and a transient dip in MOMP, but no enhanced difference in sensitivity to BH3-mimetics or increase in ATF4 expression or predicted activity in RNA-seq analysis (data not shown)

This differential regulation of adiponutrin compared with other lipases suggests that in vivo this enzyme may serve a primary function other than lipolysis

One of them is Coenzyme Q10, which can be found in every cell

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fumigatus cell lysates (Figure S7) using human IgG [anti-GliT] resulted in a 51% reduction of gliotoxin reductase (NADPH oxidase) activity (Figure 5D), in complete accordance with data in Figure 5C, further confirming enzyme specificity