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To fully understand the nature of complex and multifactorial diseases such as MASLD, it is important to consider the role of genetic and epigenetic factors as essential aspects of a broader context that includes clinical and environmental influences and their interactions when multiple metabolic pathways are involved [259]

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Across experimental models, luteolin consistently limits oxidative injury within granulosa cells, preserves mitochondrial function, and suppresses apoptosis, thereby reducing follicular atresia and supporting orderly follicular progression

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Association of High-Level MRP1 Expression With Poor Clinical Outcome in a Large Prospective Study of Primary Neuroblastoma