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The TRPM family is blocked by a variety of molecules and microenvironmental conditions (Jimenez et al., 2020)

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doi: 10.1016/j.cca.2006.06.028 75 BatciogluKMehmetNOzturkICYilmazMAydogduNErguvanRet al

Moreover, cytokines, including TNF-, IL-6, and IFN-, and the populations of infiltrated F4/80 + /CD86 + macrophages and CD3 + /CD8 + T cells in tumor tissues, were significantly upregulated in mouse serum after PCT treatment, further confirming the robust activation of the immune response (Figs

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