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Possible biological benefits under investigation include: Reduced energy intake Altered satiety signaling Modulation of body weight-related outcomes These findings are based on research studies and development hypotheses rather than established clinical outcomes

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Address correspondence to: Konstantinos Drosatos, Metabolic Biology Laboratory, Temple University School of Medicine, Center for Translational Medicine, Department of Pharmacology, 3500 North Broad Street, Philadelphia, Pennsylvania 19140, USA

Furthermore, H&E staining showed that compared to the aorta of normal aging mice, the aorta of mice treated with FOXO4-DRI was thinner, and the PWV value was lower in the ultrasound detection results, which means that the mice treated with FOXO4-DRI had better vascular elasticity and better vascular function than normal aging mice (Figures 1D,E)

Tudor, M., Jandric, I., Marovic, A., Gjurasin, M., Perovic, D., Radic, B., Blagaic, A

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