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The lack of substantial overlap between these two predominant clusters suggests that the WD/LD-T group has a distinct pattern of ASV relative abundances in its microbiome compared to the other treatment groups

Additionally, NNMT inhibition has been linked to alterations in the SAM/SAH ratio, which may influence broader epigenetic methylation patterns

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Draw the solvent : Use a syringe to measure the required amount of solvent, then inject it slowly along the side of the vial

These observations were performed by three independent physiatrists who were blinded to the treatment groups, ensuring unbiased assessment