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Treatment begins with a 2.5 mg weekly starting dose, then increases by 2.5 mg every 4 weeks until reaching the effective maintenance level between 5-15 mg weekly

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Begin with the lowest effective dose Observe response over 37 days Increase only if results plateau and no side effects are present In peptide therapy, conservative titration with consistent monitoring tends to yield better outcomes and fewer side effects than aggressive front-loading. Milekic, T