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Gooch K, Culleton BF, Manns BJ, Zhang J, Alfonso H, Tonelli M,

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The principle is based on the different membrane permeability to the membrane-impermeable fluorescent DNA intercalating agent PI which stains membrane-compromised cells (red fluorescence) [40]

GOQDs offer excellent biocompatibility, hydrophilicity, low toxicity, chemical stability, and stable fluorescence emission, making them promising alternatives to toxic semiconductor quantum dots for biomedical applications 133

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