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Despite increased expression of complex I and IV proteins with B12 supplementation and previously observed increased complex I and IV OCR in B12-supplemented, aged male mice [26], we did not observe an improvement in mitochondrial complex activity (i.e., oxygen consumption rate) in the aged female mice

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Placebo, 6.7 mg/L Zn and 0.6 mg/L of copper)

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A pharmaceutical preparation called Deltaran became available in some countries, combining DSIP with glycine for enhanced stability and effect