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In most cases, the entire amount of those antioxidants is greatly reduced (over 95%) within the cytosol, chloroplast, and mitochondria, with oxidized forms accumulating only in compartments with less efficient redox recycling mechanisms, like vacuoles and apoplasts (Noctor et al., 2018)

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The effects of selenium supplementation on antibody titres in patients with Hashimoto's thyroiditis

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Liver biopsy is impractical and unnecessary for most patients in clinical practice