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NRF2 is involved in regulating programmed functions in response to oxidative stimuli, such as autophagy, inflammasome assembly, endoplasmic reticulum stress/unfolded protein response, mitochondrial biogenesis, and stem cell regulation

Stroke-induced cell proliferation and neurogenesis decreased in the IF group, possibly related to reduced cell death

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Oleic acid exerts direct and indirect suppression of NF-B, a key inflammatory transcription factor, and reduces NLRP3 inflammasome activation, thereby limiting production of pro-inflammatory cytokines IL-1 and IL-18 [70]

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3-Methoxytyramine, an extraneuronal dopamine metabolite plays a physiological role in the brain as an inhibitory regulator of catecholaminergic activity