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Due to its application as a drug to prevent rejection after organ transplantation but also to treat autoimmune diseases, care must be taken to differentiate between intended exposure via drugs and non-intended exposure

Ethics declarations Ethics approval and consent to participate The study was approved by the Ethics Committee of Zhengzhou University Peoples Hospital

The treatment of the dimethyl-alpha-ketoglutarate group (DM-KG group) was administered intraperitoneal injections of 600 mg/kg DM-KG (Sigma-Aldrich, 349631) every other day for 28 consecutive days

This is where targeted metabolic support becomes a critical piece of the recovery puzzle

After blocking, membranes were incubated with primary antibodies against SLC7a11 (1:1000, Abcam), GPX4 (1:1,000, Abcam), and PPAR (1:1,000

Enhances moisture retention Glutathione can boost the skin's moisture retention