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(1998) Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice

KEAP1-dependent NRF2 activators Electrophilic compounds The most known NRF2 activators are electrophiles electron-deficient species able to form covalent bonds with electron-rich nucleophiles through a variety of chemical pathways which can covalently bind and modify cysteine residues in KEAP1 [273, 274]

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Further studies have shown that PKC directly phosphorylates Ser 40 within the Neh2 domain of NRF2, which is necessary for the dissociation of NRF2 from Keap1 [41]

To perform a global functional analysis of Candida species, we collected 49 publicly available genomes of different Candida strains covering 13 different species (Supplementary Table 1)

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