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The latter stimulates the efflux of damage-associated molecular patterns (DAMPs) as high-mobility group box-1, which can activate numerous receptors as receptor for advanced-glycation end-products (RAGE) and TLR (Toll-like receptor)4, creating a neuroinflammatory status [45]

Vitamin B12 is an important micronutrient that aids with proper red blood cell formation, neurological function and DNA synthesis

Mol Cancer Ther 17:497507 Chen X, Yang L, Oppenheim JJ, Howard OZ (2002) Cellular pharmacology studies of shikonin derivatives

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