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To stimulate BMDMs, cells were incubated with 50 ng ml 1 LPS ( E

Fang C, Pan J, Qu N, Lei Y, Han J, Zhang J, et al

Nat Protoc (2010) 5:170929

But it does not work for everyone, and it does not address the underlying immune dysregulation

In an autologous blood injection model of ICH, PDZ improves neurological recovery, an effect blocked by the Nrf2 inhibitor ML385, demonstrating that PPAR/Nrf2/GPX4 signaling underlies its protective mechanism (197)