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After validation, the structures of the HaloTag adducts were deposited in the PDB database under PDB codes 7ZBA (MeTRaQ-G), 7ZBB (TRaQ-G-ctrl) and 7ZBD (TRaQ-G)

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Upon prolonged ER stress, ATF6 becomes activated and can induce autophagy by activating death-associated protein kinase (DAPK), which phosphorylates Beclin1, facilitating its release from the Bcl-2 complex [36]