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The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset

Furthermore, supplementation with L-GSH in T2DM subjects, resulted in maintained levels of reduced GSH ( Figures 4FH ), while the group that received placebo had decreased levels of reduced GSH after 3 months ( Figures 4FH )

10.1016/j.molmed.2023.05.013 101 LiW.WuL.HuangC.LiuR.LiZ.LiuL.et al (2020b)

To compare gene and metabolite profiles between genotypes and time points, principal component analysis (PCA) and hierarchical clustering analysis were conducted using the procomp function and the ComplexHeatmap package in R (www.r-project.org)

AmiriFVirdisANevesMFIglarzMSeidahNGTouyzRMet alEndothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction