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10.1073/pnas.71.11.4457 135 ShiehA

In severely GH-deficient men ages 17-34 yr, on average, 10 mg MK-677 increased serum IGF-1 levels by 52%, and increased GH levels by 79%, while 50 mg MK-677 increased serum IGF-1 levels by 79%, and increased GH levels by 82% [R]

E and F, The western blot analysis of Notch2, Notch3 using Scramble, si-Notch2 or si-Notch3 in U87 (E) and U251 (F) cells

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At the same time, the emergence of stem cell technology has brought new hope for the treatment of IVDD, particularly with mesenchymal stem cells (MSCs), which have demonstrated positive effects in disc regeneration due to their excellent proliferation potential and differentiation capabilities ( This article provides a comprehensive review of recent advancements in IVDD research, with a focus on the development and application of biomaterials