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In an upcoming Phase 2 clinical trial called PUERTA, ALT-100 mAb will tested in subjects with acute respiratory distress syndrome (ARDS), a critical illness in patients with respiratory failure requiring mechanical ventilation with a 40% mortality rate

Similar content being viewed by others Introduction Chimeric antigen receptor (CAR) T-cell therapy, a treatment with T cells expressing antibody-based fusion proteins targeting tumor antigens, has brought tremendous breakthroughs in the treatment of hematological malignancies, including B-cell leukemia, lymphoma, and multiple myeloma (MM) [1,2,3,4,5,6,7]

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Respirable uranyl-vanadate-containing particulate matter derived from a legacy uranium mine site exhibits potentiated cardiopulmonary toxicity

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Glutamate and -aminobutyric acid (GABA) are the major excitatory and inhibitory neurotransmitters, respectively, in the matured central nervous system