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By contrast, class B peptide GPCRs exhibit a distinct structural architecture featuring a large N-terminal ECD that is critical for peptide ligand recognition

124 The observation that the incidence of hyperbilirubinemia in G6PD-deficient infants born in Australia to Greek immigrants is lower than that noted in deficient infants in Greece suggests that local environmental variables are probably important

System x C blockade targets cancers with mut-p53 accumulation Since cancer cells with mut-p53 accumulation are vulnerable to oxidative stress, we next sought to identify potential antioxidative stress genes which when suppressed, would preferentially kill cancer cells with stabilized mut-p53

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In their study, liposomes loaded with metal and nitroimidazole antibiotic complexes were employed to target these anaerobic bacteria, thereby inhibiting tumor growth