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*Correspondence: Weina Li, [email protected] Meng Li, [email protected] These authors have contributed equally to this work This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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GPER and bone metabolism With accelerated global aging, the incidence of metabolic bone disease (MBD) is increasing annually and has become one of the important challenges facing public health [139]

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Improving embryo viability The three antioxidants we have selected have a highly beneficial effect on embryo development when used individually and to a greater effect when in combination