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Potentially supporting lean body composition goals when medically evaluated and monitored

Deficiency in B12 disrupts these processes, leading to reduced energy production and potential neurological or cardiovascular complications

No evidence supports its use over or in addition to evidence-based orthobiologic interventions

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Response: We note that in the CY 2026 OPPS/ASC proposed rule (90 FR 33775), we proposed to utilize the same file format requirementsthe QRDA standardapplied in the Hospital IQR, OQR, and Medicare Promoting Interoperability Programs (85 FR 58940, 86 FR 42262, and 80 FR 49706, respectively)