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Could the behavioural phenotype in Tbx1 +/ mice be due to altered levels of glutamate and glutamine reported here

doi: 10.1016/j.cell.2005.10.041 74 LucasDScheiermannCChowAKunisakiYBrunsIBarrickCet al

Each CoA can be verified against its accession number at the testing lab

The TetraGFP-NLS protein showed an exclusive nuclear localization, whereas TetraGFP-NLS-NES1 and TetraGFP-NLS-NES2 displayed both cytoplasmic and nuclear signals, with a stronger cytoplasmic signal for the NES2 construct (Fig

In adults, findings have been more variable: some studies have reported increased NR3C1 methylation following early-life adversity, while others have found hypomethylation associated with suicide or post-traumatic stress disorder (PTSD) (251, 272, 273)