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reported one norbornene-derived rhodamine B, which is capable of detecting As(III) in aqueous medium up to 200 nM concentration [70]

Garlic has been shown in human and animal studies to decrease oxidative stress markers like MDA (126, 128, 133, 134, 136) and enhance the activity of antioxidant enzymes like TAC (125, 129, 134) and SOD (125, 127, 129, 133, 136)

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where the authors showed by disrupting the tensin function in human fibroblasts that late fibrillar adhesions disappeared but the early focal adhesions stayed intact indicating that tensin is necessary for adhesion maturation (Pankov et al., 2000)

In addition, PD target levels were determined based on preclinical data to allow an assessment of the relevance of the administered doses in terms of target inhibition during the Phase I clinical study and to determine the RP2D

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