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Apoptotic macrophages expressing p53 have decreased MDM2 levels

Potential risks include glucose intolerance, edema, arthralgia, carpal-tunnel symptoms, elevated IGF-1, hypersensitivity, injection-site reactions, excessive tissue growth, and possible effects on malignancy

Consequently, disruption of mitochondrial transport to the synapse is a primary driver of synaptic degeneration and eventual neuronal death (67)

Takahashi K, Tomaru A, Nishiyama N, & Horiguchi M (1986) Alcoholic cardiomyopathy: direct and indirect effects of acetaldehyde

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doi: 10.1016/j.foodhyd.2017.07.029 106