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doi: 10.3390/ijms22136995 36 YunnaCMengruHLeiWWeidongC

The accumulation of blood components in the damaged area is a key pathological feature of hemorrhagic conditions, with hemoglobin release from lysed red blood cells and subsequent degradation into heme and free iron being major contributors to iron overload in ICH (Wang and Dor, 2007)

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critical information on tissue penetration, metabolic half-lives, and clearance pathways is largely absent from the literature, undermining the ability to predict therapeutic windows or potential toxicities

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It is commonly used in skin whitening products and products to even skin tone by inhibiting the activity of tyrosinase and the generation of melanin