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Testosterone may facilitate social approach by specifically activating the amygdalae if social approach is desired (2015) www.sciencedaily.com From the article: In a double-blind, placebo-controlled study, 54 young healthy women were given 0.5 mg of testosterone (or a placebo) four hours before a brain scan

No adverse effects, allergic reactions, or irritation have been reported at concentrations up to 3%

doi:10.1186/s12881-018-0709-3

Molecules 29 (10), 2214

The metabolic reprogramming is executed by activation of several transcription factors, such as HIF, HK2, lactate dehydrogenase 5 (LDH5), lactate dehydrogenase A (LDHA), PDK1, PI3K, Akt, mTOR, EGFR, etc., which induce the Warburg effect, suppress oxidative metabolism in mitochondria, limit pyruvate entry into the tricarboxylic acid (TCA) cycle, trigger anabolism, and endorse lactate formation

The result is the removal of inflammatory molecules and calmer brain