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FMRP is one of these newly synthesized proteins and serves as a repressor of the translation of other synaptic mRNAs that encode LTD proteins such as activity-regulated cytoskeleton-associated protein (Arc), microtubule associated protein (MAP) 1B and Striatal-enriched protein tyrosine phosphatase (STEP), which mediate a-amino-3-hydroxyl-4-isoxazole propionic acid receptor (AMPAR) internalization and LTD stabilization (Bhakar et al., 2012

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Falinski MM, Plata DL, Chopra SS, Theis TL, Gilbertson LM, Zimmerman JB

doi: 10.1038/srep18061 80 FAO (2014)

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