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Description

Manifestations and mechanisms of stem cell aging

Over time, the glow fades, the tone changes, and the skin just doesnt bounce back the same way

The classic hematological abnormality in B 12 deficiency is megaloblastic anemia, possibly accompanied by leukocytopenia and/or thrombocytopenia

Cell 153 (7), 14481460

We postulated that if depletion of the UMP/UDP/UTP pool is driving this stress, then we would see similar effects with a DHODH inhibitor, BAY-2402234 (ref