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Third, 5mC-containing sequences can undergo mutations by deamination, UV exposure, or interaction with certain carcinogenic chemicals.[11] Significantly, all three changes often occur in cancer, which shows that a lack of epigenetic balance is a crucial part of cancer development.[12] Excluding CpG -rich areas, most CpGs in the genome are 80% methylated, while the usual CpG methylation level in cancer is 40%60%.[13] However, it is still unclear how DNA methylation changes occur in a cancerous epigenome and what biological effects may result from reduced methylation [Figure 1]

Homocysteine is a naturally occurring amino acid that the body produces during the methylation process

Hayes, J.D

10.2174/1381612054864894 193 VctorV

PMID: 7619388, DOI: 10.1159/000170199

Stoffgruppen (Glutathion und Anthocyane) zu einer anhaltenden Regeneration der radikal-detoxifizierenden Funktionen.In addition, there is not only a reduction in oxidized glutathione (GSSG) and a prevention and / or detoxification of glutathione radicals, but even in an oscillating reaction cycle between the two substances or groups of substances (glutathione and anthocyanins) there is a sustained regeneration of the radical detoxifying functions