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reported that treatment with daratumumab increases MM cell death, especially in the presence of a subset of CD14 + /CD16 + monocytes, and that combining daratumumab with anti-CD47 enhances the elimination of MM cells that are resistant to daratumumab alone (66)

Signs include itching, hives, trouble breathing, and swelling of the face, lips, or throat

Region-specific leptin resistance within the hypothalamus of diet-induced obese mice

Adult dogs dosed intramuscularly for three treatments at 12.5 mg/kg followed by 57 oral treatments at 12.5 mg/kg all at 12 hour intervals did not exhibit either significant clinical signs or effects upon the clinical chemistry hematological or histological parameters

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Post-surgical patients almost universally require B12 supplementation, often by injection