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Collectively, these findings indicate that DM-associated metabolic dysregulation can directly induce pulmonary vascular injury by disrupting autophagy

And the compound has a short-term safety profile, at least in qualified sourcing conditions, that warrants continued investigation rather than dismissal

doi: 10.1016/j.cnur.2018.05.004

doi: 10.3389/fphar.2021.789570 Wu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022)

Taylor WD, Aizenstein HJ, Alexopoulos GS

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