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For instance, disruption of client retrograde retrieval due to mutations in COPA, the human ortholog of -COPI, underlies the autoimmune COPA syndrome, which causes coughing, shortness of breath, lung inflammation and scarring, pulmonary hemorrhaging, and systemic autoimmune reactions such as arthritis 46

Bauer, N

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Balmaceda JP, Bernardini L, Ciuffardi I, Felix C, Ord T, Sueldo CE, et al