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There are also changes to overall brain structure, which may lead to pain when at rest

10.1038/nature12122 93 YoshiyasuN.MatsukiR.SatoM.UrushiyamaH.TodaE.TerasakiY.et al (2024)

Zhao H, Wang J, Li X et al (2021) A biocompatible theranostic agent based on stable bismuth nanoparticles for X-ray computed tomography/magnetic resonance imaging-guided enhanced chemo/photothermal/chemodynamic therapy for tumours