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On the other hand, mGluR imaging, particularly for subtypes 5 and 1, has been found effective ( Moreover, 1 H magnetic resonance spectroscopy (MRS) is also a non-invasive method for the assessment of levels of neurometabolites including glutamatergic ones in the brain ( Furthermore, one can indirectly assess the glutamatergic synapsis in the cortex using transcranial magnetic stimulation (TMS) with paired pulse protocol

The VCAM-1 signal area was determined in oval regions of interest encompassing the coronal brain section within each image, and images were manually thresholded by a blinded investigator

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20 46054616 Shidara Y, Yamagata K, Kanamori T, Nakano K, Kwong JQ, Manfredi G, Oda H, Ohta S, et al