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Reinehr T, Kleber M, Toschke AM, Woelfle J, Roth CL

We have shown for the first time that stable deletion of GSTP1 in A2780 ovarian tumour cells significantly and selectively increases sensitivity to cisplatin and carboplatin, drugs routinely used to treat ovarian cancer, a notoriously drug-resistant and clinically intractable disease

Moreover, anti-MMP-9 antibody treatment in C3HeB/FeJ mice led to the development of hypoxic TB granulomas and cavitary lesions, resulting in a lower relapse rate, although this was not significantly different [138]