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Altogether, these results suggest that Auranofin impairs the expression of genes associated with the MES phenotype

Because it promotes detoxification and alters cellular signaling, some individuals may experience a temporary exacerbation of symptomsoften colloquially referred to as a 'Herxheimer reaction' or detox flareas toxins are mobilized for excretion

Culture supernatants were collected at 36-, 48-, and 72-hours post-transfection

Cysteine 10 is critical for the activity of Ochrobactrum anthropi glutathione transferase and its mutation to alanine causes the preferential binding of glutathione to the H-site

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